hello!can someone help me solve this:

8 women and 12 men want to form a committee of 5 persons in which there are at least 2 men and 2 women.

1- In how many ways can they form the committee?

2- If Mr. X and Mrs. Y refuse to work together, how many committees can

be formed?

Four married couples have bought 8 seats in the same row for a concert. In how many di erent ways can they be seated:

1- With no restrictions.

2-If each couple is to sit together.

3- If all the men sit together next to the right of all the women.

Thank you