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Math Help - Probability of Mutation

  1. #1
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    Probability of Mutation

    The probability of a mutation happens is 10^-8.

    In a genome with 3*10^9 positions, what is the probability of it happens at least once, and the probability of it happens in a specific position of the genome ?
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  2. #2
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    Quote Originally Posted by deadlock View Post
    The probability of a mutation happens is 10^-8.

    In a genome with 3*10^9 positions, what is the probability of it happens at least once, and the probability of it happens in a specific position of the genome ?

    The distribution of the number of mutations is binomial with mean 30 and sd \approx \sqrt{30} \approx 5.5.

    So 1/2 a mutation is \approx 5 sd below the mean, so the probability of 0 mutations is essentially 0.

    RonL
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    Quote Originally Posted by CaptainBlack View Post
    The distribution of the number of mutations is binomial with mean 30 and sd \approx \sqrt{30} \approx 5.5.

    So 1/2 a mutation is \approx 5 sd below the mean, so the probability of 0 mutations is essentially 0.

    RonL
    I didnt understand your answer
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