x/4-5/8=x+3/16
This is more of a Pre-Algebra/Algebra problem than a Pre-Calculus problem.
Please learn to type in LaTex, or at the very least, use parentheses. What you posted is vague. Do you mean what DeMath posted above, or do you mean this?
$\displaystyle \frac{x}{4} - \frac{5}{8} = \frac{x + 3}{16}$
If so, you're obviously going to get a different answer. Start by multiplying both sides by 16:
$\displaystyle \begin{aligned}
4x - 10 &= x + 3 \\
3x &= 13 \\
x &= \frac{13}{3}
\end{aligned}$
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