The entire coloured area inside the square is $100$ square units.
To answer your question, you must subtract the areas:
1) the brown area,
2) the complete area inside the large complete circle,
3) the three green areas.
Now I will not work this completely for you. You can pay a homework service to do that.
The area inside the large complete circle is $(5)^2\pi$ square units
Can you explain why the brown area is $\frac{1}{4}\left(100-25\pi)\right)$ square units?
How do you find the area of one of the three green areas?