Problem: Let z = (x^5) / (y^3). Evaluate the four partial derivatives of z.

Attempt: OK so I don't really know where to begin. I'm taking a physical chemistry course, and the current homework due in a couple days is to help us brush up on our calc. I haven't taken calc in about 2 years, and the classes I DID take only barely touched on partial derivatives. I know asking for the answer is not gonna help, so is there any advice on how to start it? What should I be looking at? Any help is appreciated!