ouch! i'm assuming you mean

Basically what this is asking you to do is differentiate with respect to 60 times, then the resulting function with respect to twice, then that resulting function with respect to three times, then finally the resulting function with respect to 72 times.

in each case, i'd just do it a few times and try to pick up a pattern of what it would look like after doing it 60 and 72 times. good luck. seems like it will be a pain, but maybe not as hard as you think. maybe.