Sign changes occur whenever the sign of one factor changes.
This will happen at x= -4,-2,-1,1,3 and 5.
So check x<-4. Here all factors <0 so the expression is positive.
x<-4 positive
-4<x<-2 negative
-2<x<-1 positive
-1<x<1 negative
1<x<3 positive
3<x<5 negative
x>5 positive