Fisher's Exact Test

Hi all: I'm testing

H0: Theta = 1 vs HA: Theta > 1 for the following 2 x 2 Table:

----------- C-----NC--Total
Surgery -- 21 -- -- 2 ---23
Chemo -- 15 -- -- 3 ---18
----------------------------
Total-----36------5----41--

Basically, this table contains results of a study comparing Chemo with Surgery in treating Cancer of the Larynx. C = Cancer Controlled, NC = Non-Cancer Controlled. I'm supposed to use Fishers Exact Test and interpret results.

Using the hypergeometric distribution,

P(n11 = 21) = (23 C 21) * (18 C 15) / (41 C 36) = .275

I'm not sure how to interpret that result. I'm also supposed to find a one-sided P-value (manually) too, which I'm also unsure.

Any thoughts?