I would like to know why M_n is not isomorphic to O_n x T_n, where M_n is the group of isometries of R^n, O_n is the group of orthogonal matrices, and T_n is the group of translations in R^n.

**My attempt:** Can I show that one side is abelian, while the other group is not abelian? How do I go about doing that? Can I begin by showing that their centers are not isomorphic?